He's just awesome. Easily in my top 3 of all time. From comedy to tragedy his performances are honest and compelling. Keep up the awesome work Mr. Reilly.
Side note: If anyone leaves a comment that's just a Dr. Steve Brule (or any other John C Reilly character) quote their name will be added to a volunteer eugenics program, and they will no longer be invited to a single birthday party as long as they live because they are internet-stupid.